Tag Archives: antifungals

Antifungal Resistant Aspergillus Strain

Aspergillus was cultured from my sinuses in 2000. I have been on some sort of antifungal or another ever since. whenever we try to either lower the dose or stop, my symptoms return. I belong to a support group for Aspergillus through yahoo groups. This support group is part of the Fungal Research Trust.



Recently the trust started a blog. On September 20, 2012 a newsbite was posted about resistant strains of Aspergillus and the possibility of the causation being from farmers also using azoles (antifungals) on crops. We could be breathing in a resistant strain of Aspergillus. Knowing what I have experienced from my exposure to Aspergillus along with other molds, this is very frightening. Read the blog post at:


Clicking more will take you to the entire article.


What does flea medicine and antifungals have in common?

What does flea medicine and antifungals have in common?  What an odd question you might ask.  Well when treating animals for fleas, the medication only kills the live fleas and usually does not kill the eggs.  For this reason animals may have to be treated more than once to get rid of the fleas as the eggs continue to  hatch.

Antifungals work on the same principle.  Antifungals kill off the live fungi but does not deal with all spores that have yet to germinate and become live.  I have been treating myself with one type of antifungal or another for years.  In the beginning the fungal infection was so bad that I would experience herxheimer reactions when taking even the smallest amount of an antifungal and go into an anaphylactic reaction.

A herxheimer reaction sometimes just called a Herx is when the bacteria, or fungus in my case, start dying off they release endotoxins.  If more endotoxins are released than the body can rid itself of severe symptoms can occur.  Some of these symptoms can be fever, chills, headache, and hyperventilation.  For me the symptoms were tightness in the chest, difficulty breathing, stomach cramps, coughing, the feeling that my throat was constricted and dizziness.  More than once I had to rely on an epi-pen (epinephrine in an injectable pen) to stop the reactions and calm things down.  Of course, the downside of taking epinephrine is a faster heart rate, possible dizziness or light headedness, headache and tremors.  I had to take the epinephrine to stop one set of symptoms but then got another set in exchange.

Recently we decided to see how little antifungal I needed to avoid having a return of a major sinus infection.  I was originally on 400 mg. of compounded Miconazole.  I dropped to 300 and waited a month.  I was still ok so we dropped it to 200 for a month and I was still ok.  I dropped it to 100 mg and within a week my sinuses were inflamed and I had the beginning of an infection so we immediately put it back to 200 mg. and I am doing fine so far.

I had heard years ago when I first started researching mold, mycotoxins, illness, etc. that many people had to stay on some kind of maintenance dose the rest of their lives and found it difficult to believe.  I am now a believer.  The downside to antifungals is that you need to monitor your liver.  So far everything seems to be fine with mine.

Why did my face feel like it was being pulled apart?

Valentine’s Day 2001 was anything but romantic. I had been on the IV for a few days and the antifungal drug and oral antibiotic for close to a week. I had gone to work as usual…..Shortly around noon, my throat began to feel restricted. I tried to wait it out. Finally I phoned Dr. D. He suggested that I go to the emergency room. I drove myself to the hospital, which, I realize now, was probably not the smartest thing to do.  While waiting to be seen, I phoned Sarah. I asked her to pick up her father as soon as he got in from school and to drive him to meet me at the hospital emergency room.

The constriction in my throat began to get worse and I was beginning to have tremors. My face felt like it was being pulled apart. The ER doctor came in. I told him—in between spasms in my throat and face—that I was having an allergic reaction to one or more of the medications that I was taking. He asked what medications I was taking and why I had an IV line…..

The ER doctor had the gall to tell me that my reactions were not typical of allergic reactions. I was just having an anxiety attack.

Later the next day while Sarah was visiting and helping me make soup, I began having problems again.  In my book I continue to write:

Some of the same symptoms began while we were working on the soup. My throat began to get tight and feel constricted. We phoned Dr. D, and he told me to come to his office. Unfortunately, he was not in his local office. Sarah drove me about six miles to see him at his other office.

By the time we reached Dr. D’s office, I was beginning to have tremors. He ordered an EKG and had my blood sugar tested. My EKG was normal, as was my blood sugar level.

The tremors and spasms in my face and neck continued to get worse. This time, however, I also began to have tremors on the right side of my body. My right hand and leg would shake. During the spasms in my neck, I had difficulty breathing. The doctor’s staff would ask me questions. I would not answer right away so they would ask them again. I had no control over my body. I had to wait for the tremors and spasms to stop to answer questions. It was if I were riding a wave. I would have a spasm and tremors and then it would stop, only to start up again within seconds. It was almost like a seizure.

I was so frightened, and I hated that my Sarah had to see me in this state. I didn’t want to die here, not like this!

Dr. D ordered an ambulance to take me to the hospital. The tremors and spasms were getting out of control and I needed to be in a hospital setting. I remember hearing his nurse asking if he wanted lights and sirens. He responded yes! He wanted the ambulance there as soon as possible. Hearing the urgency in his voice only made me more terrified.       

I became increasingly sicker and had a fourth sinus surgery while in the hospital and developed so many problems that we had to stop most of my medications to see what was causing what.  I was on an oral antifungal, oral antibiotic and IV antibiotic.   After all this, I thought the worst was over and my journey towards wellness would begin.  I had no idea what was to come.   The tremors and the pulling apart feeling in my face (as if someone was taking my skin and stretching it over facial bones that were too big for it) soon came to be a common occurrence when I reacted to chemicals and molds.

It is because of the skeptics like the doctor in the ER on my first visit and those who know I have been sick but not really known what I have gone through that I have written my book.  There are still so many out there who do not believe mold can make you chronically ill and that there is such a thing as multiple chemical sensitivity.   I hope to have the final edits soon so that I can get my cover photos done and submit it.